Malignant Hyperthermia Association of the United States (MHAUS)
For more MH education and awareness, visit

If you are experiencing an MH emergency, please contact the toll-free hotline at 800.MH.HYPER (644.9737)

MHAUS guidelines
Stay current on the treatment guidelines and best practices for treating MH. View the MH Treatment Guidelines.

RYANODEX® Educational Tools and Support

Dosing and Administration Guide
Step-by-step instructions on how to administer and reconstitute RYANODEX® during an MH crisis.

MH Insights Video
Henry Rosenberg, MD, and President of the MHAUS, provides insight on the importance of timely treatment during an MH crisis. Watch the video.

Reconstitution and Administration Video
See how to quickly and easily reconstitute and administer RYANODEX® during an MH crisis. Watch the video.

MH Risk Infographic
Read about MH preparation from a broader perspective. Download the RYANODEX® MH Risk Infographic.

P&T Committee Support Kit
Download clinical information on RYANODEX® and MH treatment with dantrolene sodium.


Malignant hyperthermia data can be found in Anesthesia & Analgesia.

  • Larach MG, Gronert GA, Allen GC, Brandom BW, Lehman EB. Clinical presentation, treatment, and complications of malignant hyperthermia in North America from 1987 to 2006. Anesth Analg. 2010;110(2):498-507.
  • Riazi S, Larach MG, Hu C, Wijeysundera D, Massey C, Kraeva N. Malignant hyperthermia in Canada: characteristics of index anesthetics in 129 malignant hyperthermia susceptible probands. Anesth Analg. 2014;118(2):381-387.